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Daniel E Cohen Selected Research

Ritonavir (Norvir)

1/2020Raltegravir pharmacokinetics before and during treatment with ombitasvir, paritaprevir/ritonavir plus dasabuvir in adults with human immunodeficiency virus-1 and hepatitis C virus coinfection: AIDS Clinical Trials Group sub-study A5334s.
1/2020Hepatitis C Virus (HCV) Direct-Acting Antiviral Therapy in Persons With Human Immunodeficiency Virus-HCV Genotype 1 Coinfection Resulting in High Rate of Sustained Virologic Response and Variable in Normalization of Soluble Markers of Immune Activation.
12/2019Ombitasvir/paritaprevir/ritonavir and dasabuvir±ribavirin for chronic HCV infection in US veterans with psychiatric disorders.
2/2019Ombitasvir, Paritaprevir, Ritonavir, and Dasabuvir With or Without Ribavirin in Patients With Kidney Disease.
2/2019Effects of chronic kidney disease stage 4, end-stage renal disease, or dialysis on the plasma concentrations of ombitasvir, paritaprevir, ritonavir, and dasabuvir in patients with chronic HCV infection: pharmacokinetic analysis of the phase 3 RUBY-I and RUBY-II trials.
2/2019Efficacy and Safety of Ombitasvir/Paritaprevir/Ritonavir in Patients With Hepatitis C Virus Genotype 1 or 4 Infection and Advanced Kidney Disease.
1/2019Ombitasvir/paritaprevir/ritonavir and dasabuvir with or without sofosbuvir for patients with hepatitis C virus genotype 1 infection who failed a prior course of direct-acting antiviral therapy.
1/2019Ombitasvir, paritaprevir, and ritonavir with peginterferon-α2a plus ribavirin in treatment-experienced patients with chronic hepatitis C virus genotype 1 infection.
11/2018Ombitasvir/Paritaprevir/Ritonavir With or Without Dasabuvir and With or Without Ribavirin for Adolescents With HCV Genotype 1 or 4.
10/2018Efficacy and Safety of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir ± Ribavirin for HCV in Brazilian Adults with Advanced Fibrosis.
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Daniel E Cohen Research Topics

Disease

18Infections
01/2021 - 08/2006
8Fibrosis (Cirrhosis)
01/2020 - 01/2014
5Chronic Hepatitis C
01/2019 - 07/2013
4Acquired Immunodeficiency Syndrome (AIDS)
04/2021 - 03/2008
4Coinfection
01/2020 - 06/2003
3HIV Infections (HIV Infection)
04/2021 - 01/2020
3Hepatitis C
01/2020 - 01/2013
3Chronic Renal Insufficiency
02/2019 - 06/2016
2Chronic Kidney Failure (Chronic Renal Failure)
02/2019 - 06/2016
2Kidney Diseases (Kidney Disease)
02/2019 - 02/2019
2Anemia
01/2018 - 06/2016
1Virus Diseases (Viral Diseases)
01/2021
1Mental Disorders (Mental Disorder)
12/2019
1Substance-Related Disorders (Drug Abuse)
12/2019
1Liver Diseases (Liver Disease)
02/2019
1Hemolytic Anemia
01/2018
1Sarcoma (Soft Tissue Sarcoma)
08/2015
1Stroke (Strokes)
08/2015
1Viremia
03/2015
1Body Weight (Weight, Body)
01/2014
1Disease Progression
03/2007
1Acute-Phase Reaction
07/2004

Drug/Important Bio-Agent (IBA)

19paritaprevirIBA
01/2020 - 01/2013
18Ritonavir (Norvir)FDA Link
01/2020 - 01/2013
17ombitasvirIBA
01/2020 - 01/2014
16Antiviral Agents (Antivirals)IBA
04/2021 - 01/2013
16dasabuvirIBA
01/2020 - 01/2013
15Ribavirin (Virazole)FDA LinkGeneric
01/2020 - 01/2013
7InterferonsIBA
01/2019 - 01/2013
5Pharmaceutical PreparationsIBA
01/2021 - 08/2015
2Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2017
2RNA (Ribonucleic Acid)IBA
01/2017 - 03/2015
2Protease Inhibitors (Protease Inhibitor)IBA
01/2014 - 01/2013
2EpitopesIBA
03/2007 - 07/2004
1HLA-DR Antigens (HLA-DR)IBA
04/2021
1Raltegravir PotassiumFDA Link
01/2020
1Interleukin-6 (Interleukin 6)IBA
01/2020
1Human immunodeficiency virus 1 p16 proteaseIBA
01/2020
1Cytochrome P-450 CYP2B1 (PROD)IBA
01/2020
1Lipopolysaccharide ReceptorsIBA
01/2020
1ledipasvirIBA
01/2019
1SofosbuvirIBA
01/2019
1QuartzIBA
01/2019
1Inosine TriphosphataseIBA
01/2018
1TabletsIBA
01/2017
1ErythropoietinFDA Link
06/2016
1Clindamycin (Cleocin)FDA LinkGeneric
02/2008
1Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric
02/2007
1Anti-Bacterial Agents (Antibiotics)IBA
02/2007
1HLA-A3 Antigen (HLA A3 Antigen)IBA
07/2004
1Hepatitis B Surface Antigens (HBsAg)FDA Link
06/2003

Therapy/Procedure

11Therapeutics
04/2021 - 02/2007
2Duration of Therapy
01/2020 - 01/2017
1Renal Dialysis (Hemodialysis)
06/2016
1Highly Active Antiretroviral Therapy (HAART)
03/2008
1Ambulatory Care (Outpatient Care)
08/2006